from Tkinter import *

class App:
	def __init__(self,master):
	
		frame = Frame(master)
		frame.pack()
		
		self.button = Button(frame,text = "QUIT",fg = "red", command=frame.quit)
		self.button.pack(side=LEFT)
		
		self.hi_there = Button(frame,text="Hello",command=self.say_hi)
		self.hi_there.pack(side=LEFT)
		
	def say_hi(self):
		print("hi there, everyone!")

root = Tk()

app = App(root)

root.mainloop()

Interfaz simple de ventana con 2 botones

Python