function custom_feature_box($post_count = true) {
    if (($post_count == 1) && is_home())
        thesis_feature_box_content();
}
add_action('thesis_hook_after_post','custom_feature_box');

This example is adding a feature box after the first post. You can apply it to any of the hooks inside the loop.

Target specific post on home page

wordpress

PHP